Variations in matrix composition and GAG fine structure among scaffolds for cartilage tissue engineering
نویسندگان
چکیده
منابع مشابه
bovine articular cartilage decellularized matrix as a scaffold for use in cartilage tissue engineering
extracelllar matrix (ecm) materials from mammalian tissues have been broadly used for tissue engineering for animal models. while decellularization of tissues such as bladder, heart valve, knee meniscus and tendon has been performed, there are a few reports for articular cartilage. in this study we aimed to develop a technique to decellularize bovine articular cartilage as a biological construc...
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Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...
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her willingness to meet with me and for her expert feedback. Jeannette Yen have also been very insightful and provided me with invaluable direction during the proposal of my work. I would also like to thank my fellow past and present lab members: Dr. Lastly, I would like to thank my dear fiancée Deena for her love and support during the last part of my PhD. It was her love and kindness that kep...
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Introduction: As the ability to repair cartilage tissue in body is limited, finding a suitable method for cartilage regeneration has gained the attention of many scholars. For this purpose, scaffold structure and morphology, along with cell culture on it, can be a novel method to treat cartilage injuries, osteoarthritis. Methods: In this study, polyhydroxybutyrate (PHB) is selected as the scaf...
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the aim of the present study was to develop a tissue-engineering approach through alginate gel molding to mimic cartilage tissue in a three-dimensional culture system. the perfusion biomimetic bioreactor was designed to mimic natural joint. the shear stresses exerting on the bioreactor chamber were calculated by computational fluid dynamic (cfd). several alginate/bovine chondrocyte constructs w...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2005
ISSN: 1063-4584
DOI: 10.1016/j.joca.2005.04.020